SCHEMBL8764815

SCHEMBL8764815

CC(=O)ON=C(C(C)=O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764812 1.00 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL1783524 0.87 TSHR (0.35) ALDH1A1TSHR
SCHEMBL6567440 0.77 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL10738083 0.77 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL6567442 0.77 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL1424739 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL25404483 0.74 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL19521048 0.72 LMNA (0.35) ALDH1A1TSHR
SCHEMBL19521047 0.72 LMNA (0.35) ALDH1A1TSHR
SCHEMBL10542531 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646572-B1 Process for the preparation of ceramides QUEST INT (NL) 1997-07-23 EP disclosed