SCHEMBL8764848

SCHEMBL8764848

O=C(Oc1ccc2ccccc2c1)Oc1cccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.51
ALDH1A1 P00352 3/20 0.51
PGR P06401 1/20 0.51
GAA P10253 1/20 0.51
PTGS1 P23219 1/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 5/20 0.50
MEN1 O00255 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPT P10636 2/20 0.50
RAB9A P51151 1/20 0.50
ALOX5 P09917 2/20 0.46
PTGES O14684 1/20 0.46
MMP1 P03956 2/20 0.46
MMP12 P39900 1/20 0.46
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
MMP2 P08253 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28372648 0.95 ALDH1A1 (0.50) HSD17B10ALDH1A1PGRGAAPTGS1
SCHEMBL28372649 0.88 KMT2A (0.47) HSD17B10ALDH1A1PGRGAAPTGS1
SCHEMBL37865 0.86 ALDH1A1 (0.65) HSD17B10ALDH1A1PGRGAAPTGS1
SCHEMBL29901836 0.86 ALDH1A1 (0.65) HSD17B10ALDH1A1PGRGAAPTGS1
SCHEMBL537475 0.85 ALDH1A1 (0.56) HSD17B10ALDH1A1PGRGAAPTGS1
SCHEMBL1809377 0.84 KMT2A (0.66) HSD17B10ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL31107522 0.83 HSD17B10 (0.48) HSD17B10ALDH1A1PGRGAAPTGS1
SCHEMBL20898321 0.83 KMT2A (0.50) HSD17B10ALDH1A1PGRGAAPTGS1
SCHEMBL18817858 0.83 HSD17B10 (0.53) HSD17B10ALDH1A1PGRGAAPTGS1
SCHEMBL28688861 0.83 ALDH1A1 (0.46) HSD17B10ALDH1A1PGRGAAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0614877-B1 Process for the continuous preparation of aryle carbonates BAYER AG (DE) 1997-08-20 EP disclosed
EP-0608710-B1 Process for the continuous preparation of aryle carbonates BAYER AG (DE) 1997-07-30 EP disclosed
EP-0572870-B1 Process for the production of organic carbonates with at least one aromatic ester group BAYER AG (DE) 1996-07-17 EP disclosed
US-5523451-A Process for the continuous preparation of aryl carbonates BAYER AKTIENGESELLSCHAFT (DE) 1996-06-04 US disclosed
US-5362901-A Process for the preparation of organic carbonates having at least one aromatic ester group BAYER AKTIENGESELLSCHAFT (DE) 1994-11-08 US disclosed
EP-0614877-A1 Process for the continuous preparation of aryle carbonates BAYER AG (DE) 1994-09-14 EP disclosed
EP-0608710-A1 Process for the continuous preparation of aryle carbonates BAYER AG (DE) 1994-08-03 EP disclosed
EP-0572870-A1 Process for the production of organic carbonates with at least one aromatic ester group BAYER AG (DE) 1993-12-08 EP disclosed