SCHEMBL8764968

SCHEMBL8764968

CSc1cc(N)c(SC)c(N)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNKSR1 Q969H4 1/20 0.31
PTK2 Q05397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675667 0.80 ALDH1A1 (0.38) CNKSR1PTK2
SCHEMBL8674326 0.78 ALDH1A1 (0.43) CNKSR1
Hydrochloric Acid SCHEMBL8675812 0.78 ALDH1A1 (0.36) CNKSR1PTK2
SCHEMBL2860506 0.78 CYP3A4 (0.39) PTK2
Hydrochloric Acid SCHEMBL8671244 0.76 ALDH1A1 (0.41) CNKSR1
SCHEMBL11755246 0.76 GAA (0.35)
SCHEMBL3683818 0.72 PTK2 (0.37) CNKSR1PTK2
SCHEMBL2090059 0.72 NOS3 (0.39)
SCHEMBL688102 0.72 ALDH1A1 (0.40)
SCHEMBL2866234 0.71 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US claimed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US claimed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP claimed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO claimed
US-20130220507-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-08-29 US claimed
EP-0635034-B1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEM CO INC (US) 1997-07-30 EP claimed
EP-0635034-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM. UNIROYAL CHEM CO INC (US) 1995-01-25 EP claimed
WO-1993021247-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-28 WO claimed
CN-108973274-A It is used to prepare the adhesive composition of the compound of rubber and polar thermosetting material 普利司通美国轮胎运营有限责任公司 2018-12-11 CN disclosed
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US disclosed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US disclosed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP disclosed
US-8821663-B2 Ballistic resilient run-flat tire, kit and method thereof ARNCO (US) 2014-09-02 US disclosed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO disclosed
US-5223599-A Polyetherurethanes and alkylthioaromatic amine curing agents, which are non-carcinogenic UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-29 US disclosed
EP-0193872-B1 DI(ALKYLTHIO) DIAMINE CHAIN EXTENDERS FOR POLYURETHANE ELASTOMERS ETHYL CORPORATION (US) 1993-03-31 EP disclosed
EP-0228190-B1 RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION ETHYL CORPORATION (US) 1991-02-27 EP disclosed
EP-0228190-A2 RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production ETHYL CORPORATION (US) 1987-07-08 EP disclosed
US-4631298-A REACTION INJECTION MOLDING POLYURETHANES ETHYL CORPORATION (US) 1986-12-23 US disclosed
US-4595742-A Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine ETHYL CORPORATION (US) 1986-06-17 US disclosed