Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.80 |
| ▸ | DRD3 | P35462 | 9/20 | 0.80 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | DRD4 | P21917 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765149 | 1.00 | DRD2 (0.80) | DRD2DRD3OPRK1DRD4MAPT | |
| Bromide SCHEMBL8765845 | 0.98 | DRD2 (0.77) | DRD2DRD3OPRK1DRD4MAPT | |
| Bromide SCHEMBL8765851 | 0.98 | DRD2 (0.77) | DRD2DRD3OPRK1DRD4MAPT | |
| SCHEMBL5722322 | 0.89 | DRD2 (1.00) | DRD2DRD3OPRK1DRD4MAPT | |
| SCHEMBL30697493 | 0.89 | DRD2 (1.00) | DRD2DRD3OPRK1DRD4MAPT | |
| SCHEMBL265949 | 0.89 | DRD2 (1.00) | DRD2DRD3OPRK1DRD4MAPT | |
| SCHEMBL9135070 | 0.89 | DRD2 (1.00) | DRD2DRD3OPRK1DRD4MAPT | |
| SCHEMBL30839518 | 0.89 | DRD2 (1.00) | DRD2DRD3OPRK1DRD4MAPT | |
| Water SCHEMBL9305264 | 0.87 | DRD2 (0.96) | DRD2DRD3OPRK1DRD4MAPT | |
| Water SCHEMBL9305270 | 0.87 | DRD2 (0.96) | DRD2DRD3OPRK1DRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |