Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | GPR4 | P46093 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073205 | 0.88 | KCNH2 (0.35) | CPN1CPB2KCNH2 | |
| SCHEMBL7333024 | 0.88 | GAA (0.41) | GNAI3GNAO1GNAI1 | |
| SCHEMBL13153397 | 0.88 | KCNH2 (0.35) | CPN1CPB2KCNH2 | |
| SCHEMBL9435793 | 0.86 | GNAI3 (0.42) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7876684 | 0.84 | — | — | |
| SCHEMBL28892 | 0.82 | CPN1 (0.39) | CPN1CPB2GPR4KCNH2GNAI3 | |
| SCHEMBL6371560 | 0.80 | CPN1 (0.38) | CPN1CPB2GPR4KCNH2SLC6A2 | |
| SCHEMBL22066364 | 0.79 | CPN1 (0.41) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11892780 | 0.79 | TP53 (0.50) | — | |
| SCHEMBL6370619 | 0.79 | CPN1 (0.41) | CPN1CPB2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625509-B1 | N-alkyl substituted piperidine-derivatives with neurokinin receptor antagonist activity | ZENECA LTD (GB) | 1997-07-30 | — | — | EP | disclosed |
| US-5521199-A | TREATMENT OF ASTHMA | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0625509-A1 | N-alkyl substituted piperidine-derivatives with neurokinin receptor antagonist activity | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |