SCHEMBL8765471

SCHEMBL8765471

CC=CCCOC(=O)/C=C\C(=O)OCCC=CC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
HCAR2 Q8TDS4 7/20 0.47
MAPT P10636 2/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
TSHR P16473 5/20 0.33
ALDH1A1 P00352 4/20 0.33
HPGD P15428 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GSTP1 P09211 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467648 0.87 ATM (0.57) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL674235 0.83 TSHR (0.54) ATMHCAR2MAPTTSHRALDH1A1
SCHEMBL10947979 0.81 ALDH1A1 (0.38) ALDH1A1PPARGPPARDPPARA
SCHEMBL10947988 0.81 ALDH1A1 (0.38) ALDH1A1PPARGPPARDPPARA
SCHEMBL28576320 0.80 ATM (0.54) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4113520 0.80 ATM (0.54) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3504385 0.79 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9334949 0.79 ATM (0.39) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL15865685 0.79 ATM (0.48) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL27755971 0.79 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
US-5554695-A Styrenic copolymer and process for producing same IDEMITSU KOSAN CO. LTD. (JP) 1996-09-10 US disclosed
EP-0511407-B1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN CO (JP) 1996-05-29 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5475061-A High degree of syndiotactic configuration; using alumoxane and transition metal compound catalysts IDEMITSU KOSAN CO., LTD. (JP) 1995-12-12 US disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed