Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931322 | 1.00 | ATM (0.44) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL15536312 | 1.00 | ATM (0.44) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL18339134 | 1.00 | ATM (0.44) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL27755971 | 1.00 | ATM (0.44) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL4113520 | 0.90 | ATM (0.54) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL28576320 | 0.90 | ATM (0.54) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL28767987 | 0.89 | ATM (0.50) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL22390230 | 0.83 | HCAR2 (0.48) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL4113527 | 0.83 | HCAR2 (0.63) | ATMHCAR2ADORA3NR1I2PGR | |
| SCHEMBL22581648 | 0.83 | HCAR2 (0.48) | ATMHCAR2ADORA3NR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| CN-110891615-B | System and method for selecting and releasing fragrance | 阿甘香气及精细化学有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-108601958-B | Pro-fragrance compositions | 爱客多有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10695277-B2 | Pro-fragrance composition | AQDOT LIMITED (GB) | 2020-06-30 | — | — | US | disclosed |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-04-06 | — | — | US | disclosed |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | SENOMYX INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| EP-2769971-B1 | Novel Organoleptic Compound | INT FLAVORS & FRAGRANCES INC (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2769972-B1 | Novel organoleptic compound | INT FLAVORS & FRAGRANCES INC (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2769972-A1 | Novel organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-08-27 | — | — | EP | disclosed |
| EP-2769971-A1 | Novel Organoleptic Compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-08-27 | — | — | EP | disclosed |
| US-8785677-B1 | Organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8772533-B1 | Organoleptic compound | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20100248390-A1 | COMPOSITIONS AND METHODS FOR IDENTIFYING LIGANDS OF ODORANT RECEPTORS | DUKE UNIVERSITY (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ATM 322/4885HCAR2 2574/4885ADORA3 2392/4885 |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | ATM 1037/4885HCAR2 1934/4885ADORA3 666/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ATM 322/4885HCAR2 2574/4885ADORA3 2392/4885 |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | TRPA1, PDE6G, PDE6D | ATM 1766/4885HCAR2 522/4885ADORA3 956/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ATM 322/4885HCAR2 2574/4885ADORA3 2392/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ATM 322/4885HCAR2 2574/4885ADORA3 2392/4885 |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | ATM 1442/4885HCAR2 542/4885ADORA3 1057/4885 |
| US-10695277-B2 | Pro-fragrance composition | COPS5, COPS8, CBR3 | ATM 4249/4885HCAR2 3171/4885ADORA3 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.