Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461936 | 0.83 | HSD17B10 (0.50) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL10332960 | 0.79 | HSD17B10 (0.47) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL10332959 | 0.79 | HSD17B10 (0.47) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL6870799 | 0.79 | HSD17B10 (0.52) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL20150198 | 0.79 | HSD17B10 (0.52) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL3160352 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL10505220 | 0.75 | HPGD (0.55) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL11381869 | 0.75 | TDP1 (0.53) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL16690965 | 0.75 | HSD17B10 (0.47) | ALDH1A1TSHRHSD17B10TDP1KMT2A | |
| SCHEMBL22566 | 0.74 | HSD17B10 (0.67) | ALDH1A1TSHRHSD17B10TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | claimed |
| CN-101747342-B | Technology for synthesizing aspoxicillin | NANJING HEALTHNICE MEDICAL TECHNOLOGY CO LTD | 2013-03-06 | — | — | CN | claimed |
| CN-101747342-A | Technology for synthesizing aspoxicillin | QIAOGEN ZOU | 2010-06-23 | — | — | CN | claimed |
| CN-113999251-A | Synthetic method of aspoxicillin sodium | 海南海灵化学制药有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | disclosed |
| WO-2017004609-A1 | THIADIAZOLE MODULATORS OF S1P AND METHODS OF MAKING AND USING | EXELIXIS, INC. (US) | 2017-01-05 | — | — | WO | disclosed |
| CN-103992337-B | A kind of method preparing Aspoxicillin sodium easily | 南京优科生物医药研究有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104059087-B | A kind of synthetic method of aspoxicillin | HUNAN ER-KANG PHARMACEUTICAL CO., LTD. (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-102971318-B | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-103333180-B | Preparation method of aspoxicillin | HUNAN SANQING PHARMACEUTICAL CO., LTD. (CN) | 2014-10-15 | — | — | CN | disclosed |
| CN-104059087-A | Synthesis method of aspoxicillin | HUNAN ER KANG PHARMACEUTICAL CO LTD | 2014-09-24 | — | — | CN | disclosed |
| EP-0433655-B1 | 2-(1-substituted-2-imidazolin-2-yl)benzoic and nicotinic acids and a method for their preparation | AMERICAN CYANAMID CO (US) | 1995-01-18 | — | — | EP | disclosed |
| US-5354727-A | Herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5213607-A | Pre and post emergence herbicides | AMERICAN CYANAMID COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
| US-5062881-A | Herbicides | AMERICAN CYANAMID COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| EP-0433655-A1 | 2-(1-substituted-2-imidazolin-2-yl)benzoic and nicotinic acids and a method for their preparation | AMERICAN CYANAMID COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4719231-A | 3-[N-(mercaptoacyl)]amino-4-arylbutanoic acid derivatives and an analgesic agent comprising the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1988-01-12 | — | — | US | disclosed |
| CN-85101497-A | Process for the preparation of N-aryl-3-aryl-4, 5-dihydro-1H-pyrazole-1-carboxamides | — | 1986-07-16 | — | — | CN | disclosed |
| US-4438265-A | Esters of 7-sulfenyliminocephem-4-carboxylic acids | SANKYO COMPANY LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| US-4162251-A | Process for the preparation of β-lactam compounds | SANKYO COMPANY LIMITED (JP) | 1979-07-24 | — | — | US | disclosed |