Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150198 | 1.00 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL2461936 | 0.83 | HSD17B10 (0.50) | HSD17B10TDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL28875649 | 0.81 | GPR35 (0.62) | HSD17B10TDP1TSHRKMT2AMEN1 | |
| SCHEMBL16919574 | 0.79 | TDP1 (0.42) | HSD17B10TDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL10332959 | 0.79 | HSD17B10 (0.47) | HSD17B10TDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL876553 | 0.79 | ALDH1A1 (0.47) | HSD17B10TDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL10332960 | 0.79 | HSD17B10 (0.47) | HSD17B10TDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL16690965 | 0.79 | HSD17B10 (0.47) | HSD17B10TDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL3160352 | 0.76 | ALDH1A1 (0.46) | HSD17B10TDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL13630905 | 0.75 | TDP1 (0.53) | HSD17B10TDP1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| EP-1149094-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037464-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2000-06-29 | — | — | WO | disclosed |