Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.55 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12893176 | 0.88 | ESR1 (0.65) | HSD11B1HSD11B2ESR1ESR2HDAC4 | |
| SCHEMBL12893170 | 0.88 | ESR1 (0.65) | HSD11B1HSD11B2ESR1ESR2HDAC4 | |
| SCHEMBL12893314 | 0.85 | ESR1 (0.79) | HSD11B1HSD11B2ESR1ESR2HDAC4 | |
| SCHEMBL12893195 | 0.85 | HSD11B1 (0.45) | HSD11B1HSD11B2ESR1ESR2HDAC4 | |
| SCHEMBL19528272 | 0.85 | ESR1 (0.79) | HSD11B1HSD11B2ESR1ESR2HDAC4 | |
| SCHEMBL23221330 | 0.85 | ESR1 (0.79) | HSD11B1HSD11B2ESR1ESR2HDAC4 | |
| SCHEMBL12893194 | 0.82 | HSD11B1 (0.45) | HSD11B1HSD11B2ESR1ESR2HDAC4 | |
| SCHEMBL16029802 | 0.82 | HDAC4 (0.50) | HSD11B1HSD11B2HDAC4ACHEHTR2C | |
| SCHEMBL9149484 | 0.80 | OPRM1 (0.55) | HSD11B1HSD11B2HDAC4ACHEALDH1A1 | |
| SCHEMBL13061001 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |