Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.43 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27961305 | 0.81 | SRD5A2 (0.49) | CYP3A4PTGS1CHRNB4CHRNA3ADRA1A | |
| SCHEMBL2708239 | 0.81 | CA12 (0.54) | LMNAHIF1AKDM4E | |
| SCHEMBL4363303 | 0.80 | FFAR1 (0.56) | FFAR1ALOX5LTB4RLTB4R2IGLV6-57 | |
| SCHEMBL1070170 | 0.80 | CASR (0.50) | FFAR1ALOX5IGLV6-57LMNA | |
| SCHEMBL1070173 | 0.80 | CASR (0.50) | FFAR1ALOX5IGLV6-57LMNA | |
| SCHEMBL12182421 | 0.80 | ACHE (0.48) | FFAR1ALOX5PTGS1LTB4RLTB4R2 | |
| SCHEMBL12182460 | 0.80 | ACHE (0.48) | FFAR1ALOX5PTGS1LTB4RLTB4R2 | |
| SCHEMBL10767870 | 0.79 | FFAR1 (0.57) | FFAR1ALOX5LTB4RLTB4R2 | |
| SCHEMBL27980861 | 0.79 | ALOX5 (0.50) | FFAR1ALOX5LTB4RLTB4R2ADRA1A | |
| SCHEMBL30398332 | 0.79 | CYP3A4 (0.62) | CYP3A4CHRNB4CHRNA3LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961231-B2 | NTCP inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-03-30 | — | — | US | disclosed |
| US-20210040072-A1 | NTCP Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-02-11 | — | — | US | disclosed |
| CN-1847296-B | Polyolefin resin composition | SUMITOMO CHEMICAL CO | 2010-12-01 | — | — | CN | disclosed |
| CN-1847296-A | Polyolefin resin composition | SUMITOMO CHEMICAL CO (JP) | 2006-10-18 | — | — | CN | disclosed |
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040072-A1 | NTCP Inhibitors | HAVCR2, NPC1, HMGCR | FFAR1 2085/4885CYP3A4 739/4885ALOX5 3803/4885 |
| US-10961231-B2 | NTCP inhibitors | HAVCR2, NPC1, HMGCR | FFAR1 2085/4885CYP3A4 739/4885ALOX5 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.