Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19724354 | 0.77 | ESR1 (0.37) | KMT2A | |
| SCHEMBL6370603 | 0.76 | LMNA (0.48) | TSHRKMT2A | |
| SCHEMBL30357010 | 0.76 | KMT2A (0.52) | TSHRKMT2A | |
| SCHEMBL525257 | 0.76 | KMT2A (0.52) | TSHRKMT2A | |
| SCHEMBL28974294 | 0.74 | KMT2A (0.50) | TSHRKMT2A | |
| SCHEMBL31500776 | 0.73 | TSHR (0.41) | TSHR | |
| SCHEMBL4985623 | 0.73 | TSHR (0.41) | TSHR | |
| SCHEMBL5720313 | 0.73 | TSHR (0.36) | TSHRKMT2A | |
| SCHEMBL11971888 | 0.73 | PDE2A (0.38) | TSHRKMT2A | |
| SCHEMBL9253335 | 0.71 | ADRA2A (0.36) | TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105887127-A | Method for preparing chloromethyl pyridine derivative by electrochemical selective dechloridation | 浙江工业大学 | 2016-08-24 | — | — | CN | disclosed |
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |