SCHEMBL8765716

SCHEMBL8765716

CCc1cccc(N(c2cccc(CC)c2)c2cccc(N(c3cccc(CC)c3)c3cccc(CC)c3)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 19/20 0.47
TP53 P04637 2/20 0.44
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766587 0.94 TP53 (0.44) SIGMAR1TP53
SCHEMBL12957222 0.93 TP53 (0.54) SIGMAR1TP53CYP2D6TSHRTHPO
SCHEMBL76603 0.91 TP53 (0.52) SIGMAR1TP53CYP2D6TSHRTHPO
SCHEMBL13136839 0.91 TP53 (0.52) SIGMAR1TP53CYP2D6TSHRTHPO
SCHEMBL13479421 0.90 SIGMAR1 (0.42) SIGMAR1
SCHEMBL17678530 0.90 BCL2 (0.46) SIGMAR1TP53
SCHEMBL9487247 0.89 SIGMAR1 (0.39) SIGMAR1TP53
SCHEMBL20030125 0.88 SIGMAR1 (0.43) SIGMAR1
SCHEMBL21392008 0.88 CYP2C19 (0.44) SIGMAR1TP53
SCHEMBL13136832 0.88 CYP2C19 (0.44) SIGMAR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0420207-B1 Electrophotosensitive material and method of manufacturing the same MITA INDUSTRIAL CO LTD (JP) 1997-08-13 EP disclosed
EP-0390196-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-09-20 EP disclosed
US-5185228-A Binder resin, charge transfer material; stability MITA INDUSTRIAL CO., LTD. (JP) 1993-02-09 US disclosed
US-5128229-A Polycarbonate, m-phenylenediamine derivative MITA INDUSTRIAL CO., LTD. (JP) 1992-07-07 US disclosed
US-5059503-A Used for copying machine MITA INDUSTRIAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0390196-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed