Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | JAK2 | O60674 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2021873 | 0.94 | GAA (0.69) | GAAJAK2LMNAMAPTKDM4E | |
| SCHEMBL9045649 | 0.89 | GAA (0.82) | GAAJAK2LMNAMAPTKDM4E | |
| SCHEMBL277663 | 0.88 | GAA (0.72) | GAAJAK2LMNAMAPTKDM4E | |
| SCHEMBL31567853 | 0.88 | GAA (0.72) | GAAJAK2LMNAMAPTKDM4E | |
| SCHEMBL24011910 | 0.87 | GAA (0.78) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL9123832 | 0.87 | GAA (0.78) | GAAJAK2LMNAMAPTDRD2 | |
| Hydrochloric Acid SCHEMBL14999781 | 0.86 | KDM4E (0.72) | GAAJAK2LMNAMAPTKDM4E | |
| SCHEMBL5621969 | 0.85 | GAA (0.82) | GAAJAK2LMNAMAPTKDM4E | |
| SCHEMBL2637278 | 0.83 | GAA (0.95) | GAAJAK2LMNAMAPTKDM4E | |
| SCHEMBL10583714 | 0.82 | GAA (0.64) | GAAJAK2LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |