SCHEMBL277663

SCHEMBL277663

NCCOc1ccccc1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.72
JAK2 O60674 1/20 0.72
LMNA P02545 1/20 0.72
MAPT P10636 1/20 0.72
KDM4E B2RXH2 1/20 0.68
HTR1B P28222 2/20 0.55
TP53 P04637 2/20 0.53
MAPK1 P28482 1/20 0.53
RAB9A P51151 1/20 0.53
DRD2 P14416 1/20 0.51
DRD4 P21917 1/20 0.51
DRD3 P35462 1/20 0.51
TAAR1 Q96RJ0 2/20 0.50
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
APP P05067 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31567853 1.00 GAA (0.72) GAAJAK2LMNAMAPTKDM4E
Hydrochloric Acid SCHEMBL14999781 0.98 KDM4E (0.72) GAAJAK2LMNAMAPTKDM4E
SCHEMBL2021873 0.89 GAA (0.69) GAAJAK2LMNAMAPTKDM4E
SCHEMBL8765738 0.88 GAA (0.67) GAAJAK2LMNAMAPTKDM4E
SCHEMBL2637278 0.86 GAA (0.95) GAAJAK2LMNAMAPTKDM4E
SCHEMBL25409990 0.85 KDM4E (0.59) GAAJAK2LMNAMAPTKDM4E
SCHEMBL5621969 0.84 GAA (0.82) GAAJAK2LMNAMAPTKDM4E
SCHEMBL9045649 0.84 GAA (0.82) GAAJAK2LMNAMAPTKDM4E
SCHEMBL31050988 0.84 KDM4E (0.95) GAAJAK2LMNAMAPTKDM4E
SCHEMBL8834938 0.84 KDM4E (0.95) GAAJAK2LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119495483-B Magnetic material, preparation thereof, rotor and thermal management system 杭州千石科技有限公司 2026-05-15 CN claimed
CN-119361721-A Polymer-coated Pt/C catalyst with vacancy interlayer, and preparation method and application thereof 哈尔滨工业大学 2025-01-24 CN claimed
CN-118745658-A Electromagnetic shielding and antibacterial multifunctional nylon fiber and preparation method thereof 浙江理工大学桐乡研究院有限公司 2024-10-08 CN claimed
CN-118717544-A Amino acid ultraviolet protection composition, preparation method and application 江南大学 2024-10-01 CN claimed
CN-118725607-A Melanin and its preparation method 江南大学 2024-10-01 CN claimed
CN-115746663-B Antibacterial powder coating and preparation method thereof 廊坊市亚龙三惠科技有限公司 2023-07-25 CN claimed
CN-116103050-A Soil restoration material adopting bamboo charcoal solid powder and preparation method thereof 水之清环保(上海)股份有限公司 2023-05-12 CN claimed
CN-119495483-B Magnetic material, preparation thereof, rotor and thermal management system 杭州千石科技有限公司 2026-05-15 CN disclosed
CN-121086613-A Mortar-like water-based environment-friendly paint and preparation method thereof 成都迪泰化工有限公司 2025-12-09 CN disclosed
CN-118725607-B Melanin and its preparation method 江南大学 2025-07-18 CN disclosed
CN-119774557-A Composite heterogeneous nano material and preparation method and application thereof 长江师范学院 2025-04-08 CN disclosed
CN-119495483-A Magnetic material, preparation thereof, rotor and thermal management system 杭州千石科技有限公司 2025-02-21 CN disclosed
CN-119361721-A Polymer-coated Pt/C catalyst with vacancy interlayer, and preparation method and application thereof 哈尔滨工业大学 2025-01-24 CN disclosed
US-20030087948-A1 Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use H. LUNDBECK A/S (DK) 2003-05-08 US disclosed
EP-1274411-A1 PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE Axon Biochemicals B.V. (NL) 2003-01-15 EP disclosed
WO-2001078713-A1 PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE AXON BIOCHEMICALS B.V. (NL) 2001-10-25 WO disclosed
US-4818766-A ANTIARRHYTHMIA AGENTS, HYPOTENSIVE AGENTS, TREATMENT OF ANGINA CIBA-GEIGY CORPORATION (US) 1989-04-04 US disclosed
EP-0254682-A1 Phenoxyaliphatylphenylenoxyalkylesters and -amides CIBA-GEIGY AG (CH) 1988-01-27 EP disclosed
US-4313956-A Novel sypathomimetic amine prodrugs INTERX RESEARCH CORP. (US) 1982-02-02 US disclosed
US-4263325-A PHENOXY- AMINE DERIVATIVES AKTIEBOLAGET HASSLE (SE) 1981-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087948-A1 Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use ADRA1D, ABCE1, ADRA1B GAA 1099/4885JAK2 3977/4885LMNA 1884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.