Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8766863 | 0.95 | ADRB3 (0.51) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| SCHEMBL8766821 | 0.95 | ADRB3 (0.51) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8765612 | 0.94 | ADRB3 (0.50) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| SCHEMBL9518883 | 0.93 | ACHE (0.58) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| SCHEMBL5679478 | 0.93 | ACHE (0.58) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| SCHEMBL5681817 | 0.93 | ACHE (0.58) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9443687 | 0.92 | ACHE (0.57) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8765234 | 0.92 | ACHE (0.57) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8765229 | 0.92 | ACHE (0.57) | ADRB3ACHEPOLBALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8765354 | 0.87 | GAA (0.51) | ADRB3ACHEPOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |