SCHEMBL8765841

SCHEMBL8765841

CCCc1ccccc1C1(c2ccccc2CCC)CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.41
PGR P06401 1/20 0.35
SLC6A2 P23975 3/20 0.34
SLC6A3 Q01959 3/20 0.34
SLC6A4 P31645 2/20 0.34
SIGMAR1 Q99720 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766383 0.85 HDAC4 (0.56) HDAC4SLC6A2SLC6A3SLC6A4GRIN2D
SCHEMBL11806132 0.84 HDAC4 (0.41) HDAC4SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL29262368 0.82 HDAC4 (0.43) HDAC4
SCHEMBL16593853 0.81 HDAC4 (0.39) HDAC4SLC6A2SLC6A3SLC6A4
SCHEMBL8766761 0.81 KDM4E (0.37) HDAC4
SCHEMBL8766538 0.81 ACHE (0.35) HDAC4
SCHEMBL8767206 0.78 HRH3 (0.35) HDAC4
SCHEMBL28407415 0.78 HDAC4 (0.40) HDAC4SLC6A2SLC6A3SLC6A4GRIN2D
SCHEMBL28431231 0.78 LIPG (0.43) SLC6A2SLC6A3SLC6A4SIGMAR1
SCHEMBL9352973 0.77 CNR2 (0.40) HDAC4SLC6A2SLC6A3SLC6A4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601813-B1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORP (JP) 1997-08-13 EP disclosed
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed
US-5382688-A Diamino compounds and their production method CHISSO CORPORATION (JP) 1995-01-17 US disclosed
EP-0601813-A1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1994-06-15 EP disclosed