Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766453 | 1.00 | GRM2 (0.41) | GRM2SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL8766445 | 1.00 | GRM2 (0.41) | GRM2SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL8767227 | 0.99 | SLC6A4 (0.42) | GRM2SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL8766501 | 0.94 | HTR2A (0.40) | GRM2SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL8766910 | 0.89 | HTR2A (0.42) | SLC6A4SLC6A3SLC6A2HTR2AHTR2C | |
| SCHEMBL2858683 | 0.87 | OPRL1 (0.45) | GRM2SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL1812661 | 0.85 | OPRL1 (0.46) | GRM2SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL8766925 | 0.85 | GRM2 (0.40) | GRM2HTR2AHTR2COPRM1OPRL1 | |
| SCHEMBL8767267 | 0.85 | GRM2 (0.40) | GRM2HTR2AHTR2COPRM1OPRL1 | |
| SCHEMBL8767231 | 0.85 | GRM2 (0.40) | GRM2HTR2AHTR2COPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |