Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766925 | 1.00 | GRM2 (0.40) | GRM2HTR2CHTR2AOPRM1HDAC4 | |
| SCHEMBL8767231 | 1.00 | GRM2 (0.40) | GRM2HTR2CHTR2AOPRM1HDAC4 | |
| SCHEMBL8766830 | 0.99 | HTR2C (0.40) | GRM2HTR2CHTR2AOPRM1HDAC4 | |
| SCHEMBL8766547 | 0.94 | HTR2C (0.40) | GRM2HTR2CHTR2AOPRM1HDAC4 | |
| SCHEMBL8767236 | 0.88 | HTR2C (0.42) | HTR2CHTR2AOPRM1HDAC4HSD11B1 | |
| SCHEMBL8766445 | 0.85 | GRM2 (0.41) | GRM2HTR2CHTR2AOPRM1OPRK1 | |
| SCHEMBL8767096 | 0.85 | KCNH2 (0.35) | OPRM1CYP3A4CYP2C8S1PR3OPRK1 | |
| SCHEMBL8765866 | 0.85 | GRM2 (0.41) | GRM2HTR2CHTR2AOPRM1OPRK1 | |
| SCHEMBL8766518 | 0.85 | KCNH2 (0.35) | OPRM1CYP3A4CYP2C8S1PR3OPRK1 | |
| SCHEMBL8766453 | 0.85 | GRM2 (0.41) | GRM2HTR2CHTR2AOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |