Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767227 | 0.96 | SLC6A4 (0.42) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL8765866 | 0.94 | GRM2 (0.41) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL8766445 | 0.94 | GRM2 (0.41) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL8766453 | 0.94 | GRM2 (0.41) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL8766910 | 0.91 | HTR2A (0.42) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL8766534 | 0.86 | HTR2A (0.45) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL8766547 | 0.84 | HTR2C (0.40) | HTR2AHTR2CSLC6A3SLC6A2CYP1A2 | |
| SCHEMBL8766392 | 0.83 | HRH3 (0.37) | CYP1A2OPRM1OPRL1OPRK1 | |
| SCHEMBL1812661 | 0.82 | OPRL1 (0.46) | HTR2AHTR2CHTR2BSLC6A4SLC6A3 | |
| SCHEMBL8766440 | 0.82 | HRH3 (0.39) | CYP1A2OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |