SCHEMBL8765898

SCHEMBL8765898

CCC1CCC(c2ccc(Cc3ccc(N)cc3)c(C)c2)(c2ccc(Cc3ccc(N)cc3)c(C)c2)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
CYP3A4 P08684 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 2/20 0.32
ALOX12 P18054 2/20 0.32
RXRA P19793 1/20 0.32
NPSR1 Q6W5P4 1/20 0.30
CYP19A1 P11511 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
SLC5A1 P13866 1/20 0.30
SLC5A2 P31639 1/20 0.30
GNRHR P30968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767232 0.91 ALDH1A1 (0.32) ALDH1A1L3MBTL1ESR1ESR2CYP3A4
SCHEMBL8766084 0.89 CYP1A2 (0.32) ALDH1A1L3MBTL1CYP19A1CYP1A2
SCHEMBL8766377 0.88 CYP19A1 (0.33) CYP3A4CYP19A1CYP2D6CYP2C9CYP2C19
SCHEMBL8766463 0.88 ALDH1A1 (0.35) ALDH1A1L3MBTL1ESR1ESR2CYP3A4
SCHEMBL8766456 0.87 CYP19A1 (0.34) CYP3A4CYP19A1CYP2D6CYP2C9CYP2C19
SCHEMBL8766004 0.87 CYP19A1 (0.34) CYP3A4CYP19A1CYP2D6CYP2C9CYP2C19
SCHEMBL8766439 0.87 CYP19A1 (0.34) CYP3A4CYP19A1CYP2D6CYP2C9CYP2C19
SCHEMBL8767260 0.87 ALDH1A1 (0.34) ALDH1A1L3MBTL1CYP3A4TSHRTDP1
SCHEMBL8766803 0.86 ALDH1A1 (0.33) ALDH1A1L3MBTL1CYP3A4TSHRTDP1
SCHEMBL8766417 0.85 ALDH1A1 (0.33) ALDH1A1L3MBTL1CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601813-B1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORP (JP) 1997-08-13 EP disclosed
US-5382688-A Diamino compounds and their production method CHISSO CORPORATION (JP) 1995-01-17 US disclosed
EP-0601813-A1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1994-06-15 EP disclosed