SCHEMBL8766004

SCHEMBL8766004

CCCCCCCC1CCC(c2ccc(Cc3ccc(N)cc3)c(C)c2)(c2ccc(Cc3ccc(N)cc3)c(C)c2)CC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 11/20 0.34
GRM2 Q14416 1/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
S1PR3 Q99500 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766456 1.00 CYP19A1 (0.34) CYP19A1GRM2CYP3A4CYP2C8CYP2D6
SCHEMBL8766439 1.00 CYP19A1 (0.34) CYP19A1GRM2CYP3A4CYP2C8CYP2D6
SCHEMBL8766377 0.99 CYP19A1 (0.33) CYP19A1GRM2CYP3A4CYP2C8CYP2D6
SCHEMBL8766084 0.96 CYP1A2 (0.32) CYP19A1
SCHEMBL8767232 0.91 ALDH1A1 (0.32) CYP19A1CYP3A4
SCHEMBL8765898 0.87 ALDH1A1 (0.34) CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL4318693 0.86 CYP19A1 (0.42) CYP19A1GRM2CYP3A4CYP2C8CYP2D6
SCHEMBL3441837 0.86 CYP19A1 (0.42) CYP19A1GRM2CYP3A4CYP2C8CYP2D6
SCHEMBL6360834 0.86 CYP19A1 (0.42) CYP19A1GRM2CYP3A4CYP2C8CYP2D6
SCHEMBL5179632 0.85 CYP19A1 (0.41) CYP19A1GRM2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601813-B1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORP (JP) 1997-08-13 EP disclosed
US-5382688-A Diamino compounds and their production method CHISSO CORPORATION (JP) 1995-01-17 US disclosed
EP-0601813-A1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1994-06-15 EP disclosed