Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765558 | 0.82 | TAAR1 (0.43) | TAAR1CYP1A2CTSKCACNA1BHDAC1 | |
| SCHEMBL8766759 | 0.81 | MTNR1A (0.44) | TAAR1CTSKCACNA1BMEN1KMT2A | |
| SCHEMBL29059722 | 0.80 | HDAC1 (0.52) | TAAR1CYP1A2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL23231470 | 0.78 | HDAC1 (0.56) | TAAR1CYP1A2HDAC1HDAC6 | |
| SCHEMBL27578835 | 0.77 | CTBP2 (0.55) | CYP1A2ALDH1A1HTTSMN1; SMN2CTBP2 | |
| SCHEMBL2026436 | 0.77 | PPARA (0.48) | TAAR1SLC7A5CYP1A2CACNA1BCTBP2 | |
| SCHEMBL2026435 | 0.77 | PPARA (0.48) | TAAR1SLC7A5CYP1A2CACNA1BCTBP2 | |
| SCHEMBL13349249 | 0.76 | TAAR1 (0.68) | TAAR1IDO1AGXT | |
| SCHEMBL27397323 | 0.75 | ITGA4 (0.47) | TAAR1CACNA1BIDO1ALDH1A1HTT | |
| SCHEMBL13225835 | 0.75 | HDAC1 (0.47) | TAAR1CYP1A2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |