SCHEMBL8765969

SCHEMBL8765969

CCCC1CCC(c2ccc(Cc3ccc(N)cc3)c(CC)c2)(c2ccc(Cc3ccc(N)cc3)c(CC)c2)CC1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 9/20 0.32
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
DHFR P00374 1/20 0.32
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766443 0.92 ALDH1A1 (0.31) ALDH1A1L3MBTL1
SCHEMBL8767260 0.91 ALDH1A1 (0.34) CYP19A1ALDH1A1L3MBTL1DHFRCYP3A4
SCHEMBL8767232 0.88 ALDH1A1 (0.32) CYP19A1ALDH1A1L3MBTL1CYP3A4TSHR
SCHEMBL8765909 0.87 ALDH1A1 (0.31) ALDH1A1L3MBTL1
SCHEMBL8765946 0.86 ALDH1A1 (0.34) CYP19A1ALDH1A1L3MBTL1DHFRCYP3A4
SCHEMBL5178327 0.85 ALDH1A1 (0.42) CYP19A1ALDH1A1L3MBTL1CYP3A4TSHR
SCHEMBL8766417 0.84 ALDH1A1 (0.33) CYP19A1ALDH1A1L3MBTL1CYP3A4TSHR
SCHEMBL8767280 0.82 ALDH1A1 (0.51) CYP19A1ALDH1A1L3MBTL1DHFRCYP3A4
SCHEMBL6368356 0.82 ALDH1A1 (0.40) CYP19A1ALDH1A1L3MBTL1CYP3A4TSHR
SCHEMBL6368359 0.82 ALDH1A1 (0.40) CYP19A1ALDH1A1L3MBTL1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601813-B1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORP (JP) 1997-08-13 EP disclosed
US-5382688-A Diamino compounds and their production method CHISSO CORPORATION (JP) 1995-01-17 US disclosed
EP-0601813-A1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1994-06-15 EP disclosed