Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | TDO2 | P48775 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080074 | 0.92 | IDO1 (0.64) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL11922749 | 0.90 | TPSAB1 (0.62) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL17368069 | 0.90 | TPSAB1 (0.62) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL3273999 | 0.87 | HTT (0.60) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL15044828 | 0.85 | TPSAB1 (0.57) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL17086813 | 0.85 | TPSAB1 (0.59) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL24588670 | 0.83 | IDO1 (0.52) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL24588711 | 0.83 | IDO1 (0.52) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL7490523 | 0.82 | IDO1 (0.49) | IDO1TDO2HTTTPSAB1TGM2 | |
| SCHEMBL7490519 | 0.82 | IDO1 (0.49) | IDO1TDO2HTTTPSAB1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664796-B1 | METHOD OF PREPARING AMINOALKYLHYDANTOINS AND AMINOALKYL-ALPHA-AMINOACIDS | DEGUSSA (DE) | 1997-08-06 | — | — | EP | disclosed |
| US-5608076-A | Method of preparing amionoakylhydantoins and aminoalkyl-alpha-amino acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0664796-A1 | METHOD OF PREPARING AMINOALKYLHYDANTOINS AND AMINOALKYL--g(a)-AMINOACIDS. | DEGUSSA (DE) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008974-A1 | METHOD OF PREPARING AMINOALKYLHYDANTOINS AND AMINOALKYL-α-AMINOACIDS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |