SCHEMBL8766210

SCHEMBL8766210

[AlH3].[CH2]C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.45
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
MAPK1 P28482 1/20 0.39
CYP1A2 P05177 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
PTPN1 P18031 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127186 0.97 KCNN4 (0.47) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL28757123 0.93 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL9052398 0.83 NOTUM (0.48) KCNN4ALDH1A1TSHRCYP11B1CYP11B2
SCHEMBL3173030 0.76 KCNN4 (0.47) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL8522135 0.75 CA4 (0.54)
SCHEMBL9595065 0.75 CA4 (0.54)
SCHEMBL28672611 0.73 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL11439383 0.73 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL28159184 0.73 ALDH1A1 (0.57) ALDH1A1TSHRMAPK1
SCHEMBL1864749 0.72 KCNN4 (0.57) KCNN4ALDH1A1TSHRMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0518021-B1 Method for the production of alpha, omega-unsaturated oligomers containing methylidene groups from alpha, omega-diolefines in the presence of organoaluminium compounds as catalyst ROEHM GMBH (DE) 1997-08-20 EP disclosed
EP-0518021-A2 Method for the production of alpha, omega-unsaturated oligomers containing methylidene groups from alpha, omega-diolefines in the presence of organoaluminium compounds as catalyst RÖHM GMBH (DE) 1992-12-16 EP disclosed