SCHEMBL9149386

SCHEMBL9149386

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9147496 0.97 THRB (0.32) LMNATHRB
SCHEMBL9149051 0.95
SCHEMBL9148413 0.89
SCHEMBL11511027 0.86 LMNA (0.42) LMNATHRB
SCHEMBL9589771 0.86 LMNA (0.42) LMNATHRB
SCHEMBL3313899 0.86 LMNA (0.42) LMNATHRB
SCHEMBL29163536 0.86 LMNA (0.42) LMNATHRB
SCHEMBL21355 0.86 LMNA (0.42) LMNATHRB
SCHEMBL11509926 0.86 LMNA (0.42) LMNATHRB
SCHEMBL3629816 0.86 LMNA (0.42) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1098085-A Chlorofluoroether compositions and preparation method thereof MINNESOTA MINING & MFG (US) 1995-02-01 CN claimed
WO-1994013612-A1 CHLOROFLUOROETHER COMPOSITIONS AND PREPARATION THEREOF MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-23 WO claimed
US-5420359-A Blood substitutes, solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-30 US disclosed
CN-1098085-A Chlorofluoroether compositions and preparation method thereof MINNESOTA MINING & MFG (US) 1995-02-01 CN disclosed
WO-1994013612-A1 CHLOROFLUOROETHER COMPOSITIONS AND PREPARATION THEREOF MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-23 WO disclosed