Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.59 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 8/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827676 | 0.93 | NR5A1 (0.62) | LTA4HNR5A1ESR1CYP19A1ESR2 | |
| SCHEMBL5492018 | 0.91 | NR5A1 (0.66) | LTA4HNR5A1ESR1CYP19A1ESR2 | |
| SCHEMBL8765479 | 0.91 | NR5A1 (0.66) | LTA4HNR5A1ESR1CYP19A1ESR2 | |
| SCHEMBL1437186 | 0.88 | CYP19A1 (0.70) | LTA4HNR5A1ESR1CYP19A1ESR2 | |
| SCHEMBL991452 | 0.88 | TAAR1 (0.56) | LTA4H | |
| Hydrochloric Acid SCHEMBL1437387 | 0.86 | CYP19A1 (0.68) | LTA4HNR5A1ESR1CYP19A1ESR2 | |
| Hydrochloric Acid SCHEMBL6258205 | 0.85 | TAAR1 (0.54) | LTA4H | |
| SCHEMBL2470706 | 0.85 | NR5A1 (0.75) | LTA4HNR5A1ESR1ESR2CYP1A2 | |
| SCHEMBL2473527 | 0.85 | LTA4H (0.68) | LTA4HNR5A1ESR1ESR2CYP1A2 | |
| SCHEMBL7882892 | 0.84 | ESR1 (0.56) | LTA4HNR5A1ESR1CYP19A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663290-A1 | POLYMETHINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | Illumina Cambridge Limited (GB) | 2020-06-10 | — | — | EP | disclosed |
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-4263325-A | PHENOXY- AMINE DERIVATIVES | AKTIEBOLAGET HASSLE (SE) | 1981-04-21 | — | — | US | disclosed |