SCHEMBL991452

SCHEMBL991452

NCCCOc1ccc(OCCCN)cc1

nearest known ligand 0.77

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.56
LTA4H P09960 2/20 0.54
PLA2G2A P14555 1/20 0.54
KCNA3 P22001 1/20 0.50
PRSS1 P07477 1/20 0.48
TMPRSS2 O15393 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6258205 0.97 TAAR1 (0.54) TAAR1LTA4HPLA2G2AKCNA3PRSS1
SCHEMBL9618305 0.92 CYP3A4 (0.50) TAAR1LTA4HPLA2G2A
SCHEMBL13178113 0.90 TDP1 (0.55) TAAR1LTA4HPLA2G2A
SCHEMBL14870900 0.88 APP (0.50) TAAR1LTA4HPLA2G2A
SCHEMBL1249273 0.88 MAOB (0.53)
SCHEMBL8766239 0.88 LTA4H (0.59) LTA4H
SCHEMBL2470401 0.88 DRD2 (0.59) TAAR1
SCHEMBL1010741 0.88 TAAR1 (0.54) TAAR1
SCHEMBL1010758 0.88 MAOB (0.52) TAAR1
SCHEMBL8432804 0.88 DRD4 (0.50) TAAR1LTA4HPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9714339-B2 Rubber composition comprising an epoxy resin and a polyimine hardener COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-07-25 US disclosed
US-9663633-B2 Composition based on natural rubber and on a polyaldimine compound COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-05-30 US disclosed
US-9566828-B2 Composition based on natural rubber and a polyimine compound MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2017-02-14 US disclosed
EP-2451656-B1 composition based on natural rubber and a polyimine compound MICHELIN & CIE (FR) 2015-11-25 EP disclosed
US-20150183983-A1 RUBBER COMPOSITION COMPRISING AN EPOXY RESIN AND A POLYIMINE HARDENER MICHELIN RECHERCHE ET TECHNIQUE, S.A. (CH) 2015-07-02 US disclosed
EP-2877526-A1 RUBBER COMPOSITION COMPRISING AN EPOXY RESIN AND A POLYIMINE HARDENER Compagnie Générale des Etablissements Michelin (FR) 2015-06-03 EP disclosed
US-9006321-B2 Composition made from natural rubber and a polyimine compound COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-04-14 US disclosed
EP-2451658-B1 COMPOSITION MADE FROM NATURAL RUBBER AND A POLYIMINE COMPOUND MICHELIN & CIE (FR) 2014-09-10 EP disclosed
WO-2014016344-A1 RUBBER COMPOSITION COMPRISING A LIGNIN-BASED RESIN COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2014-01-30 WO disclosed
WO-2014016346-A1 RUBBER COMPOSITION COMPRISING AN EPOXY RESIN AND A POLYIMINE HARDENER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2014-01-30 WO disclosed
EP-0158247-B1 PAPER-MAKING AUXILIARY AGENT BAYER AG (DE) 1988-01-07 EP disclosed
US-4689374-A Water soluble polyamidoaminepolyamine having weight average molecular weight of at least 5×105 W. R. GRACE & CO. (US) 1987-08-25 US disclosed
US-4673729-A Paper auxiliary from condensation product of aliphatic polyol-ether-amine and compound polyfunctional toward amino groups BAYER AKTIENGESELLSCHAFT (DE) 1987-06-16 US disclosed
EP-0158247-A1 Paper-making auxiliary agent BAYER AG (DE) 1985-10-16 EP disclosed
US-4384110-A POLYALKYLENE-AMINES, PAPERMAKING BAYER AKTIENGESELLSCHAFT (DE) 1983-05-17 US disclosed
US-4348514-A ACCELERATION OF DRAINAGE IN PAPERMAKING BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US disclosed
US-4319019-A RETENTION AIDS AND DRAINAGE ACCELERATORS IN PAPERMAKING BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4250298-A RETENTION AGENTS AND DRAINAGE ACCELERATORS FOR PAPERMAKING BAYER AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4250299-A RETENTION AGENTS AND DRAINAGE ACCELERATORS FOR PAPERMAKING BAYER AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4051166-A Araliphatic diisocyanates THE UPJOHN COMPANY (US) 1977-09-27 US disclosed