SCHEMBL8766537

SCHEMBL8766537

CCCc1cc(C2(c3ccc(Cc4ccc(N)cc4)c(CCC)c3)CCCCC2)ccc1Cc1ccc(N)cc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ESR1 P03372 3/20 0.36
ESR2 Q92731 3/20 0.36
LMNA P02545 3/20 0.36
ALOX12 P18054 3/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
PPARA Q07869 1/20 0.32
SLC5A1 P13866 1/20 0.31
SLC5A2 P31639 1/20 0.31
CYP19A1 P11511 1/20 0.31
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767280 0.89 ALDH1A1 (0.51) ALDH1A1L3MBTL1ESR1ESR2LMNA
SCHEMBL8766407 0.86 ALDH1A1 (0.33) ALDH1A1L3MBTL1CYP3A4TSHRTDP1
SCHEMBL8766417 0.86 ALDH1A1 (0.33) ALDH1A1L3MBTL1CYP3A4TSHRTDP1
SCHEMBL8766443 0.84 ALDH1A1 (0.31) ALDH1A1L3MBTL1SLC5A1SLC5A2
SCHEMBL8766394 0.82 ALDH1A1 (0.53) ALDH1A1L3MBTL1ESR1ESR2LMNA
SCHEMBL8766411 0.80 ALDH1A1 (0.53) ALDH1A1L3MBTL1ESR1ESR2LMNA
SCHEMBL11206599 0.78 TSHR (0.46) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL8766410 0.77 ALDH1A1 (0.42) ALDH1A1L3MBTL1ESR1ESR2LMNA
SCHEMBL8102180 0.77 CYP3A4 (0.50) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL8765551 0.77 CYP3A4 (0.50) ALDH1A1CYP3A4TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601813-B1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORP (JP) 1997-08-13 EP disclosed
US-5382688-A Diamino compounds and their production method CHISSO CORPORATION (JP) 1995-01-17 US disclosed
EP-0601813-A1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1994-06-15 EP disclosed