Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766830 | 0.96 | HTR2C (0.40) | HTR2CHTR2ACYP1A2HDAC4HSD11B1 | |
| SCHEMBL8766925 | 0.94 | GRM2 (0.40) | HTR2CHTR2AHDAC4HSD11B1OPRM1 | |
| SCHEMBL8767231 | 0.94 | GRM2 (0.40) | HTR2CHTR2AHDAC4HSD11B1OPRM1 | |
| SCHEMBL8767267 | 0.94 | GRM2 (0.40) | HTR2CHTR2AHDAC4HSD11B1OPRM1 | |
| SCHEMBL8767236 | 0.91 | HTR2C (0.42) | HTR2CHTR2AHDAC4HSD11B1OPRM1 | |
| SCHEMBL8766350 | 0.86 | HTR2C (0.45) | HTR2CHTR2AHDAC4HSD11B1OPRM1 | |
| SCHEMBL8766392 | 0.84 | HRH3 (0.37) | CYP1A2OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL8766501 | 0.84 | HTR2A (0.40) | HTR2CHTR2ACYP1A2OPRM1OPRK1 | |
| SCHEMBL8766440 | 0.83 | HRH3 (0.39) | CYP1A2OPRM1OPRK1OPRL1DRD2 | |
| SCHEMBL8094488 | 0.83 | CYP1A2 (0.42) | CYP1A2OPRM1OPRL1CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |