SCHEMBL8766566

SCHEMBL8766566

Cc1cc(Cc2ccc(C3(c4ccc(Cc5ccc(N)c(C)c5)cc4)CCCCC3)cc2)ccc1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ESR1 P03372 5/20 0.44
ESR2 Q92731 5/20 0.44
SKP2 Q13309 1/20 0.41
ACHE P22303 1/20 0.40
LMNA P02545 4/20 0.39
ALOX12 P18054 4/20 0.39
MAPT P10636 2/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
CYP3A4 P08684 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
PPARA Q07869 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766334 0.84 SKP2 (0.39) ALDH1A1L3MBTL1ESR1ESR2SKP2
SCHEMBL8765913 0.83 SKP2 (0.41) ALDH1A1ESR1ESR2SKP2MAPT
SCHEMBL8766914 0.82 ALDH1A1 (0.45) ALDH1A1L3MBTL1ESR1ESR2ACHE
SCHEMBL806949 0.82 ESR1 (0.62) ALDH1A1L3MBTL1ESR1ESR2ACHE
SCHEMBL8766224 0.82 ALDH1A1 (0.47) ALDH1A1L3MBTL1ESR1ESR2LMNA
SCHEMBL8766410 0.80 ALDH1A1 (0.42) ALDH1A1L3MBTL1ESR1ESR2SKP2
SCHEMBL8765791 0.80 SKP2 (0.41) ALDH1A1ESR1ESR2SKP2MAPT
SCHEMBL3482071 0.80 SKP2 (0.59) ALDH1A1ESR1ESR2SKP2MAPT
SCHEMBL1305524 0.79 ALDH1A1 (0.77) ALDH1A1L3MBTL1ESR1ESR2LMNA
SCHEMBL9122568 0.78 SKP2 (0.46) ALDH1A1ESR1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601813-B1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORP (JP) 1997-08-13 EP disclosed
US-5382688-A Diamino compounds and their production method CHISSO CORPORATION (JP) 1995-01-17 US disclosed
EP-0601813-A1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1994-06-15 EP disclosed