Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 5/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766658 | 0.99 | MEN1 (0.46) | MEN1KMT2AGAAFDPSGGPS1 | |
| SCHEMBL8616827 | 0.93 | GAA (0.47) | MEN1KMT2AGAAFDPSGGPS1 | |
| SCHEMBL8766041 | 0.86 | FDPS (0.42) | MEN1KMT2AFDPSGGPS1SIGMAR1 | |
| SCHEMBL8766488 | 0.86 | MEN1 (0.43) | MEN1KMT2AGAAFDPSGGPS1 | |
| SCHEMBL8766155 | 0.85 | HMGCR (0.42) | MEN1KMT2AGAAFDPSGGPS1 | |
| SCHEMBL7119208 | 0.84 | HMGCR (0.43) | MEN1KMT2AGAAFDPSGGPS1 | |
| SCHEMBL8766532 | 0.83 | HMGCR (0.45) | MEN1KMT2AGAAFDPSGGPS1 | |
| SCHEMBL8766734 | 0.83 | ESRRG (0.41) | MEN1KMT2AGAALMNARECQL | |
| SCHEMBL8766181 | 0.82 | GAA (0.50) | MEN1KMT2AGAAFDPSGGPS1 | |
| SCHEMBL8766645 | 0.81 | FDPS (0.41) | MEN1KMT2AGAAFDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |