Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766047 | 0.86 | GAA (0.46) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8766658 | 0.83 | MEN1 (0.46) | GAAMEN1KMT2AKDM4EFDPS | |
| SCHEMBL8766760 | 0.82 | MEN1 (0.45) | GAAMEN1KMT2AKDM4EFDPS | |
| SCHEMBL8616827 | 0.80 | GAA (0.47) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10024125 | 0.77 | ALDH1A1 (0.63) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11578296 | 0.75 | GAA (0.54) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8766488 | 0.74 | MEN1 (0.43) | GAAMEN1KMT2AKDM4EFDPS | |
| SCHEMBL8766605 | 0.73 | FDPS (0.41) | GAAMEN1KMT2AFDPSLMNA | |
| SCHEMBL9315265 | 0.73 | ALDH1A1 (0.57) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8766040 | 0.73 | ALDH1A1 (0.53) | GAAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |