SCHEMBL8766780

SCHEMBL8766780

Cc1ccc(C(=O)c2ccc(Oc3ccc(S(=O)(=O)c4ccc(Oc5cccc6c(C)cccc56)cc4)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
GFER P55789 1/20 0.42
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
KMT2A Q03164 2/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
MAPK1 P28482 1/20 0.39
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
POLB P06746 2/20 0.39
APEX1 P27695 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
MMP13 P45452 1/20 0.39
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13670303 0.94 HTT (0.54) HTTSMN1; SMN2L3MBTL1TDP1GFER
SCHEMBL822847 0.84 LMNA (0.53) HTTSMN1; SMN2ESR1ESR2KMT2A
SCHEMBL822653 0.84 HTT (0.65) HTTSMN1; SMN2L3MBTL1TDP1ESR1
SCHEMBL822651 0.83 HTT (0.67) HTTSMN1; SMN2L3MBTL1TDP1GFER
SCHEMBL12769554 0.83 HTT (0.67) HTTSMN1; SMN2L3MBTL1TDP1GFER
SCHEMBL822865 0.83 HTT (0.67) HTTSMN1; SMN2L3MBTL1TDP1GFER
SCHEMBL12769555 0.82 ALDH1A1 (0.47) HTTSMN1; SMN2ESR1ESR2KMT2A
SCHEMBL12769551 0.82 HTT (0.62) HTTSMN1; SMN2L3MBTL1TDP1ESR1
SCHEMBL2628157 0.81 CYP1A2 (0.43) HTTSMN1; SMN2ESR1ESR2KMT2A
SCHEMBL9914249 0.79 HTT (0.58) HTTSMN1; SMN2L3MBTL1TDP1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8916672-B2 Transparent polyarylene ether polymer with high heat resistance and method for preparing the same ICUF-HYU (Industry-University Cooperation Foundation Hanyang University) (KR) 2014-12-23 US disclosed
US-20120130041-A1 Transparent Polyarylene Ether Polymer With High Heat Resistance And Method For Preparing The Same IUCF-HYU (Industry-University Coperation Foundatio Hanyang University (KR) 2012-05-24 US disclosed