Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.34 |
| ▸ | HLCS | P50747 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8110089 | 0.92 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL9657952 | 0.76 | CRBN (0.35) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL24756756 | 0.74 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10489330 | 0.74 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10794652 | 0.74 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8767797 | 0.72 | ITGB1 (0.38) | ALDH1A1 | |
| SCHEMBL8094790 | 0.72 | — | — | |
| SCHEMBL18888757 | 0.71 | NPC1 (0.41) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28660448 | 0.71 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL28660449 | 0.71 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013484-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-09 | — | — | WO | disclosed |
| US-4353825-A | 5,6-Dehydropenicillins | SNAMPROGETTI, S.P.A. (IT) | 1982-10-12 | — | — | US | disclosed |
| US-4353825-A | 5,6-Dehydropenicillins | SNAMPROGETTI, S.P.A. (IT) | 1982-10-12 | — | — | US | disclosed |
| US-4288366-A | Method of preparation of 5,6-dehydropenicillins | SNAMPROGETTI, S.P.A. (CH) | 1981-09-08 | — | — | US | disclosed |
| US-4288366-A | Method of preparation of 5,6-dehydropenicillins | SNAMPROGETTI, S.P.A. (CH) | 1981-09-08 | — | — | US | disclosed |
| US-4133807-A | 4-Thioxo-2-azetidinones | SNAMPROGETTI, S.P.A. (IT) | 1979-01-09 | — | — | US | disclosed |
| US-4133807-A | 4-Thioxo-2-azetidinones | SNAMPROGETTI, S.P.A. (IT) | 1979-01-09 | — | — | US | disclosed |