SCHEMBL8767230

SCHEMBL8767230

Fc1cc(-c2ccc(CC[C@H]3CC[C@H](CC4CCCC4)CC3)cc2)cc(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.39
MAOB P27338 3/20 0.35
AAK1 Q2M2I8 1/20 0.34
DAO P14920 1/20 0.33
BRS3 P32247 2/20 0.33
CTSC P53634 1/20 0.32
F10 P00742 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767228 1.00 GPR84 (0.39) GPR84MAOBAAK1DAOBRS3
SCHEMBL19720332 0.93 GPR84 (0.39) GPR84MAOBAAK1DAOBRS3
SCHEMBL20805115 0.87 GPR84 (0.39) GPR84MAOBDAOBRS3CTSC
SCHEMBL8027622 0.84 GPR84 (0.40) GPR84MAOBCTSCF10HRH3
SCHEMBL13345628 0.84 GPR84 (0.40) GPR84MAOBCTSCF10HRH3
SCHEMBL12999140 0.84 GPR84 (0.40) GPR84MAOBCTSCF10HRH3
SCHEMBL9504614 0.84 GPR84 (0.40) GPR84MAOBCTSCF10HRH3
SCHEMBL9763604 0.84 HRH3 (0.45) GPR84MAOBCTSCF10HRH3
SCHEMBL8814984 0.84 GPR84 (0.40) GPR84MAOBCTSCF10HRH3
SCHEMBL9763594 0.84 HRH3 (0.45) GPR84MAOBCTSCF10HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789067-A1 Cyclopentyl derivatives useful as liquid crystals Rolic AG (CH) 1997-08-13 EP disclosed