SCHEMBL19720332

SCHEMBL19720332

Fc1cc(-c2ccc(CCC3CCCCC3)cc2)cc(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.39
DAO P14920 2/20 0.38
MAOB P27338 3/20 0.38
BRS3 P32247 2/20 0.37
HRH3 Q9Y5N1 3/20 0.37
AAK1 Q2M2I8 1/20 0.36
HRH4 Q9H3N8 1/20 0.35
CTSD P07339 1/20 0.35
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767228 0.93 GPR84 (0.39) GPR84DAOMAOBBRS3HRH3
SCHEMBL8767230 0.93 GPR84 (0.39) GPR84DAOMAOBBRS3HRH3
SCHEMBL20805115 0.91 GPR84 (0.39) GPR84DAOMAOBBRS3HRH3
SCHEMBL19720358 0.88 CYP17A1 (0.44) GPR84DAOMAOBBRS3HRH3
SCHEMBL1628510 0.85 HRH3 (0.45) HRH3AAK1PDGFRBPDGFRA
SCHEMBL17070199 0.85 F10 (0.32) GPR84DAOMAOBBRS3PDGFRB
SCHEMBL16978491 0.85 GPR84 (0.37) GPR84DAOMAOBBRS3AAK1
SCHEMBL8814984 0.85 GPR84 (0.40) GPR84MAOBHRH3
SCHEMBL13345628 0.85 GPR84 (0.40) GPR84MAOBHRH3
SCHEMBL9504614 0.85 GPR84 (0.40) GPR84MAOBHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3985085-A2 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2022-04-20 EP disclosed
EP-3666853-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2021-06-16 EP disclosed
EP-3666853-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-06-17 EP disclosed
EP-3327102-B1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2020-04-15 EP disclosed
EP-2698414-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2019-03-13 EP disclosed
EP-3327102-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2018-05-30 EP disclosed
EP-2889357-B1 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2018-02-21 EP disclosed
EP-2855630-B1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2017-12-20 EP disclosed