Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 4/20 | 0.48 |
| ▸ | THRA | P10827 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18035912 | 0.81 | SLC7A5 (0.48) | SLC7A5USP2KDM4EALOX15RECQL | |
| SCHEMBL38804 | 0.80 | SLC7A5 (0.49) | SLC7A5USP2KDM4EALOX15RECQL | |
| SCHEMBL11434038 | 0.80 | SLC7A5 (0.50) | SLC7A5USP2KDM4EALOX15RECQL | |
| SCHEMBL38803 | 0.80 | SLC7A5 (0.49) | SLC7A5USP2KDM4EALOX15RECQL | |
| SCHEMBL2703289 | 0.79 | SLC7A5 (0.55) | SLC7A5PTGS1MAPTPKMCYP2C9 | |
| SCHEMBL38535 | 0.79 | SLC7A5 (0.55) | SLC7A5PTGS1MAPTPKMCYP2C9 | |
| SCHEMBL19667341 | 0.79 | SLC7A5 (0.55) | SLC7A5PTGS1MAPTPKMCYP2C9 | |
| SCHEMBL5281836 | 0.78 | KDM4E (0.50) | SLC7A5USP2KDM4EALOX15RECQL | |
| Hydrochloric Acid SCHEMBL10477485 | 0.77 | SLC7A5 (0.53) | SLC7A5PTGS1MAPTPKMCYP2C9 | |
| Hydrochloric Acid SCHEMBL10477486 | 0.77 | SLC7A5 (0.53) | SLC7A5PTGS1MAPTPKMCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787010-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-06 | — | — | EP | disclosed |