Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 7/20 | 0.38 |
| ▸ | ACHE | P22303 | 7/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767377 | 1.00 | PTGS1 (0.43) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8767383 | 1.00 | PTGS1 (0.43) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8924155 | 0.89 | PPARA (0.42) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8924165 | 0.89 | PPARA (0.42) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8923656 | 0.86 | PSEN1 (0.38) | MEN1MAPTKMT2ATDP1PPARA | |
| SCHEMBL8923653 | 0.86 | PSEN1 (0.38) | MEN1MAPTKMT2ATDP1PPARA | |
| SCHEMBL8923654 | 0.86 | PSEN1 (0.38) | MEN1MAPTKMT2ATDP1PPARA | |
| SCHEMBL8767480 | 0.79 | ALOX5 (0.51) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8767474 | 0.79 | ALOX5 (0.51) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8768719 | 0.78 | ALOX5 (0.49) | PTGS1PTGS2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | claimed |
| US-5627205-A | ANTILIPEMIC AGENTS AND ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 1997-05-06 | — | — | US | claimed |
| US-5627205-A | ANTILIPEMIC AGENTS AND ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 1997-05-06 | — | — | US | disclosed |