SCHEMBL8923653

SCHEMBL8923653

CCOCOc1c(C)c(C)c2c(c1C)CCC(C)(/C=C\Cc1ccc(OC(C)(C)C(=O)O)cc1)O2

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 7/20 0.38
PPARG P37231 10/20 0.35
PPARA Q07869 7/20 0.35
PPARD Q03181 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8923654 1.00 PSEN1 (0.38) PSEN1PPARGPPARAPPARDMEN1
SCHEMBL8923656 1.00 PSEN1 (0.38) PSEN1PPARGPPARAPPARDMEN1
SCHEMBL8767377 0.86 PTGS1 (0.43) PPARGPPARAPPARDMEN1MAPT
SCHEMBL8767383 0.86 PTGS1 (0.43) PPARGPPARAPPARDMEN1MAPT
SCHEMBL8767394 0.86 PTGS1 (0.43) PPARGPPARAPPARDMEN1MAPT
SCHEMBL8925722 0.81 PSEN1 (0.44) PSEN1PPARGPPARAPPARDMEN1
SCHEMBL8925726 0.81 PSEN1 (0.44) PSEN1PPARGPPARAPPARDMEN1
SCHEMBL8049826 0.80 PSEN1 (0.41) PSEN1PPARA
SCHEMBL8924155 0.75 PPARA (0.42) PPARGPPARAMEN1MAPTKMT2A
SCHEMBL8924165 0.75 PPARA (0.42) PPARGPPARAMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627205-A ANTILIPEMIC AGENTS AND ANTIOXIDANTS ADIR ET COMPAGNIE (FR) 1997-05-06 US disclosed