Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407495 | 0.87 | CYP1A2 (0.37) | SMN1; SMN2MEN1KMT2AGPR174TRPA1 | |
| SCHEMBL7903540 | 0.80 | ESR1 (0.52) | SMN1; SMN2MEN1KMT2AGPR174EGFR | |
| SCHEMBL11051492 | 0.78 | POLB (0.44) | SMN1; SMN2MEN1KMT2AGPR174EGFR | |
| SCHEMBL11144218 | 0.78 | CYP1A2 (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8897839 | 0.78 | RAPGEF4 (0.47) | SMN1; SMN2GPR174TRPA1EGFRALDH1A1 | |
| SCHEMBL11419588 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AGPR174EGFR | |
| SCHEMBL14415825 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2AGPR174EGFR | |
| SCHEMBL11512360 | 0.77 | ALDH1A1 (0.54) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9979180 | 0.77 | NR1H4 (0.55) | SMN1; SMN2MEN1KMT2AGPR174EGFR | |
| SCHEMBL13344096 | 0.76 | ESR1 (0.45) | SMN1; SMN2MEN1KMT2AGPR174TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789685-A1 | GUANIDINE SALT DERIVATES AND USE AS CHARGE CONTROL AGENTS | ZENECA LIMITED (GB) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014294-A1 | GUANIDINE SALT DERIVATES AND USE AS CHARGE CONTROL AGENTS | ZENECA LIMITED (GB) | 1996-05-17 | — | — | WO | disclosed |