Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767535 | 1.00 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DHCRTR1 | |
| SCHEMBL8768471 | 0.99 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DHCRTR1 | |
| SCHEMBL8768462 | 0.99 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DHCRTR1 | |
| SCHEMBL8767319 | 0.89 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DHCRTR1 | |
| SCHEMBL8767318 | 0.88 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DHCRTR1 | |
| SCHEMBL8768474 | 0.83 | SIGMAR1 (0.36) | PDE4APDE4BPDE4CPDE4DTDP1 | |
| SCHEMBL8768483 | 0.83 | SIGMAR1 (0.36) | PDE4APDE4BPDE4CPDE4DTDP1 | |
| SCHEMBL8768294 | 0.82 | HCRTR1 (0.41) | HCRTR1HCRTR2MOGAT2 | |
| SCHEMBL8768291 | 0.82 | HCRTR1 (0.41) | HCRTR1HCRTR2MOGAT2 | |
| SCHEMBL8767598 | 0.82 | SIGMAR1 (0.33) | PDE4APDE4BPDE4CPDE4DTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |