Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.63 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.63 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517972 | 0.96 | LTB4R (0.63) | LTB4RLTB4R2PLA2G4BFFAR1SRD5A2 | |
| SCHEMBL11684213 | 0.94 | PLA2G4B (0.69) | LTB4RLTB4R2PLA2G4BFFAR1AKR1B1 | |
| SCHEMBL11683055 | 0.88 | PLA2G4B (0.61) | LTB4RLTB4R2PLA2G4BFFAR1SRD5A2 | |
| SCHEMBL8219005 | 0.86 | PLA2G4B (0.83) | PLA2G4BLMNATSHR | |
| SCHEMBL7750520 | 0.86 | PLA2G4B (0.60) | LTB4RLTB4R2PLA2G4BFFAR1SRD5A2 | |
| SCHEMBL3334872 | 0.86 | FFAR1 (0.76) | LTB4RLTB4R2FFAR1AKR1B1ALOX15 | |
| SCHEMBL11597039 | 0.85 | PLA2G4B (0.59) | LTB4RLTB4R2PLA2G4BFFAR1SRD5A2 | |
| SCHEMBL1285778 | 0.85 | PLA2G4B (0.77) | PLA2G4BLMNATSHR | |
| SCHEMBL10728695 | 0.85 | PLA2G4B (0.59) | LTB4RLTB4R2PLA2G4BFFAR1LTA4H | |
| SCHEMBL1162418 | 0.85 | PLA2G4B (0.59) | LTB4RLTB4R2PLA2G4BFFAR1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |