Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.34 |
| ▸ | AR | P10275 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769022 | 0.86 | PGR (0.47) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8767962 | 0.76 | PGR (0.32) | PGRNR3C1AR | |
| SCHEMBL8767750 | 0.73 | PGR (0.31) | PGRNR3C1AR | |
| SCHEMBL8768210 | 0.73 | NR3C1 (0.32) | PGRNR3C1AR | |
| SCHEMBL8767961 | 0.71 | PGR (0.48) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8767722 | 0.71 | PGR (0.48) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8768235 | 0.71 | PGR (0.33) | PGRNR3C1AR | |
| SCHEMBL8767815 | 0.70 | PGR (0.49) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8767965 | 0.69 | NR3C1 (0.46) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8767796 | 0.69 | PGR (0.55) | PGRNR3C1ARCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | claimed |
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | disclosed |