Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxirane SCHEMBL11687716 | 0.92 | TSHR (0.37) | TSHRNR1H2NR1H3CHRM2HTR1A | |
| SCHEMBL11676201 | 0.91 | AGXT (0.37) | TSHRNR1H2NR1H3BCHECYP2C19 | |
| SCHEMBL11690661 | 0.89 | CHRNB2 (0.46) | SLC6A2SLC6A4SLC6A3MAPTMEN1 | |
| SCHEMBL11675958 | 0.88 | AOC3 (0.45) | SLC6A4BCHEAOC3IDO1CNR2 | |
| SCHEMBL11674436 | 0.87 | BCHE (0.39) | TSHRCHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11677195 | 0.87 | IDO1 (0.44) | MAPTCYP2D6TAAR1TP53IDO1 | |
| SCHEMBL11679587 | 0.87 | TP53 (0.44) | TSHRSLC6A2SLC6A4BCHEMAPT | |
| SCHEMBL11677210 | 0.86 | TSHR (0.42) | TSHRSLC6A2SLC6A4ADRA1ASLC6A3 | |
| SCHEMBL11676389 | 0.85 | TAAR1 (0.41) | TSHRSLC6A2SLC6A4MAPTTAAR1 | |
| SCHEMBL11675106 | 0.85 | CYP3A4 (0.43) | TSHRMAPTTAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4370158-A | — | — | None | — | — | JP | disclosed |
| EP-0519459-B1 | Disperse dye mixture | DYSTAR JAPAN LTD (JP) | 1997-09-03 | — | — | EP | disclosed |
| US-5304222-A | Monoazo benzothiazole disperse dye mixture | HOECHST MITSUBISHI KASEI CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0519459-A2 | Disperse dye mixture | DyStar Japan Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| JP-H04370158-A | DISPERSE DYE MIXTURE | MITSUBISHI KASEI HOECHST KK | 1992-12-22 | — | — | JP | disclosed |
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |