Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677195 | 0.92 | IDO1 (0.44) | TP53MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL11675780 | 0.88 | KDM4E (0.46) | TP53MAPTALDH1A1HTTMEN1 | |
| SCHEMBL8767732 | 0.87 | TSHR (0.42) | TP53MAPTMEN1KMT2AIDO1 | |
| SCHEMBL11676389 | 0.85 | TAAR1 (0.41) | MAPTIDO1TSHRSLC6A2SLC6A4 | |
| SCHEMBL11676201 | 0.84 | AGXT (0.37) | RAB9ANPC1BCHETSHR | |
| SCHEMBL8435490 | 0.84 | MAPT (0.42) | TP53MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL11675474 | 0.84 | MAOB (0.49) | IDO1BCHE | |
| SCHEMBL10788304 | 0.82 | MAPT (0.43) | TP53MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL11675526 | 0.81 | MAPT (0.46) | TP53MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL8849983 | 0.81 | BCHE (0.32) | MAPTHTTBCHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |