Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.32 |
| ▸ | PGR | P06401 | 7/20 | 0.32 |
| ▸ | AR | P10275 | 5/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767931 | 0.84 | NR3C1 (0.42) | CYP3A4NR3C1PGRARDDB1 | |
| SCHEMBL8767814 | 0.75 | — | — | |
| SCHEMBL8767823 | 0.73 | PGR (0.40) | CYP3A4NR3C1PGRAR | |
| SCHEMBL8768906 | 0.69 | — | — | |
| SCHEMBL8768195 | 0.69 | PGR (0.36) | CYP3A4NR3C1PGRAR | |
| SCHEMBL8768993 | 0.69 | PGR (0.38) | CYP3A4NR3C1PGRAR | |
| SCHEMBL8768846 | 0.65 | — | — | |
| SCHEMBL8650538 | 0.63 | PGR (0.50) | CYP3A4NR3C1PGRAR | |
| SCHEMBL8768030 | 0.62 | NR3C1 (0.41) | CYP3A4NR3C1PGRAR | |
| SCHEMBL8767749 | 0.62 | NR3C1 (0.49) | CYP3A4NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | claimed |
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5426102-A | Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-20 | — | — | US | disclosed |