Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 8/20 | 0.59 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.59 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189304 | 0.91 | CA1 (0.61) | LPLLIPGRARBCA1CA2 | |
| SCHEMBL6557463 | 0.90 | LPL (0.62) | LPLLIPGRARBCA1CA2 | |
| SCHEMBL9399967 | 0.82 | RARB (0.52) | LPLLIPGRARBCNR1CNR2 | |
| SCHEMBL9493977 | 0.81 | LPL (0.62) | LPLLIPGRARBCA1CA2 | |
| SCHEMBL15725334 | 0.81 | RARB (0.52) | LPLLIPGRARBCNR1CNR2 | |
| SCHEMBL16377224 | 0.80 | RARB (0.51) | RARBCNR1CNR2ALOX5CHKA | |
| SCHEMBL9662918 | 0.80 | RARB (0.51) | RARBCNR1CNR2ALOX5CHKA | |
| SCHEMBL9664422 | 0.80 | RARB (0.51) | RARBCNR1CNR2ALOX5CHKA | |
| SCHEMBL9512294 | 0.80 | RARB (0.51) | RARBCNR1CNR2ALOX5CHKA | |
| SCHEMBL10603849 | 0.80 | RARB (0.51) | RARBCNR1CNR2ALOX5CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998540-B2 | Substituted anthracenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-08-16 | — | — | US | disclosed |
| US-7998540-B2 | Substituted anthracenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-08-16 | — | — | US | disclosed |
| US-20070014934-A1 | Substituted anthracenes | MERCK PATENT GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20070014934-A1 | Substituted anthracenes | MERCK PATENT GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| EP-0440643-B1 | FLUORINATED 4''-CYANO SUBSTITUTED TERPHENYLS | SECR DEFENCE BRIT (GB) | 1997-09-03 | — | — | EP | disclosed |
| US-5312563-A | Liquid crystals for optical apparatus | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE U.K. OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1994-05-17 | — | — | US | disclosed |
| EP-0440643-A1 | FLUORINATED 4''-CYANO SUBSTITUTED TERPHENYLS. | SECR DEFENCE BRIT (GB) | 1991-08-14 | — | — | EP | disclosed |
| WO-1989012621-A1 | FLUORINATED 4''-CYANO SUBSTITUTED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1989-12-28 | — | — | WO | disclosed |