Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ADH1A | P07327 | 6/20 | 0.35 |
| ▸ | ADH1C | P00326 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281135 | 0.89 | ADH1A (0.41) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL9283784 | 0.87 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9284267 | 0.86 | ADH1A (0.38) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL9283447 | 0.85 | CYP1A2 (0.35) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL9278278 | 0.85 | ADH1A (0.44) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL9278394 | 0.83 | ADH1C (0.34) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL13683429 | 0.82 | CYP1A2 (0.33) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL24927577 | 0.81 | SLC6A2 (0.33) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL9281036 | 0.79 | SLC6A2 (0.33) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL9283512 | 0.78 | HRH3 (0.42) | CYP2D6CYP1A2CYP2C19CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638537-B1 | Process for producing cyclobutanones | SUMITOMO CHEMICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5420356-A | Process for producing cyclobutanones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0638537-A1 | Process for producing cyclobutanones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-02-15 | — | — | EP | disclosed |